• SIRS [temperature >38° or <36°C (>100.4° or 96.8°F), Pulse >90, Tachypnea >24, ↑ WBC >12,000]• Hemoconcentration (Hct >44%)
• BISAP
• (B) Blood urea nitrogen (BUN) >22 mg%
• (I) Impaired mental status
• (S) SIRS: 2/4 present
• (A) Age >60 years
• (P) Pleural effusion
• Organ Failure
• Cardiovascular: systolic BP <90 mmHg, heartrate >130
• Pulmonary: PaO2 <60 mmHg
• Renal serum creatinine >2.0 mg%